In 2003, senior toxicologists from one of Illuminaries’ long-standing clients, Syngenta Ltd, began work as members of an international task force, looking for improved ways of performing chemical product safety testing. A key task assigned to the Syngenta scientists was the development of a database that would allow the ILSI (International Life Sciences Institute) Task Force members retrospectively to analyse the safety testing outcome for a wide range of chemicals that are currently available in markets throughout the world.
Syngenta called on the expertise of Illuminaries to help them put the finishing touches to the database which was subsequently dubbed SABRE (Safety Assessment By Refined Experimentation). For the past two years, SABRE has been used extensively by the Task Force to help develop new principles for safety testing and risk assessment based on analysis of the hazard data relating to just 64 sample chemicals.
The positive value of the Task Force’s efforts has now been recognised by the USEPA (US Environmental Protection Agency) and, at the specific request of that most prominent organisation, Syngenta has agreed to make a gift of the SABRE database to the USEPA so that evaluation of the potential benefits of the new principles can be extended by the analysis of additional chemicals using data drawn from that organisation’s extensive chemical hazard data banks.
As one of the Syngenta Task Force members remarked, “The sort of data and analyses that SABRE delivers is quite different from the type of IT solution that Illuminaries normally supply to Syngenta, yet they came up trumps to help us deliver this database to the Task Force, the outcome of whose endeavours we feel will provide a most significant improvement in the approach our industry takes in the safety assessment of its products”.
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Latest NewsMajor milestone passed with QM Application
In October 2014, the first Dean’s Report generated entirely from the database was submitted to GMCNational HCV Database - One Year On
In the first 12 months, the centres have recruited over 3000 patients into the study, close to a third of the way to the target of 10,000* and apart from a dip across the Christmas period, the cohort is growing at approximately 100 new patients /week. The number of centres across the UK has also grown, from the original 18 to almost 40. To date the system has scaled up nicely to accommodate the additional load, with no loss of performance evident.read more
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"The system is looking great. You’ve done what the previous contractor couldn’t do"
Sylvia Ward, Deputy Chief Executive, Age Concern Sheffield
"Illuminaries provided creative and imaginative solutions to our data needs and have designed a database that is straightforward to use and has flexible search methods"
Paula Walker, Sheffield and Rotherham Asbestos Group
"You were provided with quite a complicated design for an e-commerce site, they created the 'shop' whilst keeping the design as we wanted. They also provided great value for money."
Lucia Kempsey, Bettyjoy
"I really have appreciated the time and trouble you’ve taken to help me set up, especially as I’m so unused to using computers!"
Kathryn Yates, Children’s Food Company
"We had been thinking of implementing an online system to manage course approvals for some time but options were limited due to security considerations. Illuminaries were able to deliver a solution that works within our IT structure and meets all of our requirements."
Daniel Kaye, PDO SYEM
"Illuminaries were fully accommodating to all my needs and have more than delivered on what I had hoped"
Stephen Radley, Consultant Obstetrician, Sheffield Teaching Hospitals
"As you are planning to get Tony to set your database up, you can be confident that the system will work. Tony also ran the Trent HCV database for a number of years, which generated over 25 peer-reviewed publications"
Will Irving, Professor of Virology, University of Nottingham
"I felt it was very productive today and you really have done an amazing job so far with this, it is beyond the expectations I had and to see it in today’s format was really positive"
Vicky Jones, Quality Co-ordinator, Health Education England
"Thanks so much for the quality database. It is a great piece of work. I am demonstrating it today at Willerby and am sure everyone will be impressed."
Julie Platts, Quality Manager, Health Education Yorkshire and the Humber
"[The QM application is] a really powerful development that allows timely review of concerns, streamlining engagement between the Trust and HEYH so helping in the accuracy of reporting and feedback the GMC"
"You people are so helpful"
John Sellars, ICT Consulting
"The good work done by Illuminaries was highlighted by everyone (at the launch event). I personally would like to highlight the extra mile you went to get to this point. So a very special thanks to you both [Tony and Jim]"
Mohamed Naeem, Child Protection Specialist, UNICEF Maldives Country Office
"I would like to express my thanks to all of you as well as Illuminaires for their dedication and patience in delivering a user sensitive system that will help in transforming the work of the Government to plan and effectively deliver protection measures to the troubled communities and families in Maldives"
Manssor Ali - UNICEF, New York
"The very odd occasion I have required assistance, you have been very responsive in helping me resolve the problem"
Joe Wright, Momentum Transport
"Illuminaries provided a systematic and logical approach through the workshops to help clarify the data requirements and functionality of the system that would meet our business needs. This approach saved time and ensured both parties were clear about what was required"
Rosemary Clark, Objective 1
"I have just input the first patient onto the [Cirrhosis] database. Nice and easy, straight forward and only took 10 mins if that."
Andrea Bennett, Deputy Nurse Manager / STOP HCV Project Lead
"So far it’s been remarkably painless going live, so I just want to say thank you for your fantastic work. We’ve had some really positive comments, and I don’t think there have been any negative ones."
Katharine Wilkie, Finance Manager, SYFAB
"The flexibility demonstrated by Illuminaries, their readiness to consider and their ability to implement appropriate, alternative technologies into the laboratory’s business IT systems have proved to be of considerable help during a time of hectic and often profound business change."
Business Systems Manager, Syngenta